Emerging Indianapolis Startups to Watch in 2023

Indianapolis Startups

Indianapolis is a city that is thriving with a vibrant startup ecosystem. In 2023, there are several exciting startups in Indianapolis that are making waves in various industries. From biotechnology to supply chain management and business management, these startups are bringing innovative ideas and solutions to the table.

With strong funding support and a supportive startup community, these emerging Indianapolis startups are poised for success. Whether it’s developing precision endocrine therapeutics, revolutionizing supply chain technology, providing multi-unit business management platforms, or creating customer acquisition software with artificial intelligence, these startups are pushing the boundaries of what’s possible.

In this article, we will explore some of the top emerging startups in Indianapolis in 2023. These startups are definitely worth keeping an eye on as they contribute to the growth of the city’s economy and cement Indianapolis’ position as a hub for innovation and entrepreneurship.

Key Takeaways:

  • The Indianapolis startup scene in 2023 is vibrant and diverse, spanning industries such as biotechnology, supply chain management, business management, and technology.
  • MBX Biosciences is a top biotech startup in Indianapolis, focusing on developing therapies for rare endocrine diseases.
  • PAXAFE is an emerging supply chain startup in Indianapolis, offering intelligent hardware and data algorithms for more efficient supply chain management.
  • Woven provides a multi-unit business management platform for franchisees and independent owners in industries such as retail, spa, salon, and fitness.
  • DemandJump specializes in customer acquisition software that utilizes artificial intelligence to maximize marketing strategies.

Top Biotech Startup in Indianapolis: MBX Biosciences

MBX Biosciences, a leading biotechnology company based in Carmel, Indiana, is making waves in the field of endocrine therapeutics. With a strong focus on developing innovative therapies for rare endocrine diseases where treatment options are limited, MBX Biosciences is poised to revolutionize the biotech industry. Founded in 2018, the company has already secured remarkable funding of $115 million to advance their groundbreaking Precision Endocrine Peptides.

Advancing Endocrine Therapeutics

The team at MBX Biosciences is driven by a mission to improve the lives of individuals suffering from rare endocrine disorders. These conditions often lack effective treatment options, leaving patients with limited options and significant medical challenges. With their cutting-edge research and development efforts, MBX Biosciences aims to bridge this gap and provide much-needed solutions.

The company’s Precision Endocrine Peptides offer a promising approach to treating rare endocrine diseases. By targeting specific molecular mechanisms and pathways, MBX Biosciences is working towards developing tailored therapies that address the underlying causes of these conditions.

MBX Biosciences has assembled a team of world-class scientists and experts who bring diverse expertise and experience to the table. Through collaborations with leading researchers, medical professionals, and patient advocacy groups, the company is able to leverage the latest knowledge and insights to drive their research forward.

Aside from their innovative approach to endocrine therapeutics, MBX Biosciences also prioritizes patient-centricity. They understand the unique challenges faced by individuals with rare endocrine diseases and are dedicated to improving diagnosis, treatment, and overall quality of life for these patients.

Funding and Future Prospects

The significant funding that MBX Biosciences has secured demonstrates the confidence and support it has received from investors. With $115 million in funding, the company has the resources to continue advancing its groundbreaking research and development initiatives.

MBX Biosciences’ cutting-edge work in endocrine therapeutics positions it as a key player in the biotech industry, both in Indianapolis and beyond. As they continue to make strides in developing effective treatments for rare endocrine diseases, MBX Biosciences is undoubtedly a top biotech startup to watch in the coming years.

Key Highlights of MBX Biosciences
Year Founded Funding Raised Focus Area
2018 $115 million Endocrine therapeutics

Top Supply Chain Startup in Indianapolis: PAXAFE

PAXAFE, an Indianapolis-based startup, is revolutionizing supply chain management with its innovative approach and cutting-edge technology. Leveraging intelligent hardware, prediction models, and data algorithms, PAXAFE provides comprehensive supply chain solutions that ensure the timely and secure delivery of goods.

At the heart of PAXAFE’s operations is its supply chain technology, which optimizes every step of the logistics process. By analyzing data and using advanced algorithms, PAXAFE streamlines operations, minimizes bottlenecks, and reduces the risk of delays or disruptions.

One of PAXAFE’s standout offerings is its parcel IoT solutions. These solutions leverage Internet of Things (IoT) technology to provide real-time tracking and monitoring of parcels throughout the supply chain. Through sensor-equipped devices, PAXAFE enables businesses to track the location, condition, and security of their shipments, giving them full visibility and control over their valuable assets.

In early 2022, PAXAFE secured $1.5 million in funding to support its expansion plans and further enhance its supply chain solutions. This investment is a testament to the confidence that investors have in PAXAFE’s innovative approach and its potential to disrupt the industry.

With its focus on supply chain technology and its dedication to providing reliable, efficient, and secure logistics solutions, PAXAFE is undoubtedly one of the top startups in Indianapolis to watch in 2023. As the demand for seamless supply chain management continues to grow, PAXAFE is well-positioned to lead the way with its transformative solutions.

Top Business Management Startup in Indianapolis: Woven

Woven is a startup that provides a multi-unit business management platform for franchisees and independent owners. Their platform streamlines operations and helps manage people, locations, and operations from a single place. With Woven’s integrated approach, businesses can simplify their processes and focus on growing their operations.

Woven caters to a range of industries, including spas, salons, retail stores, gyms, and fitness centers. Their customizable solutions are designed to meet the specific needs of each business, providing the tools and features necessary for success. By centralizing operations, Woven empowers franchisees and owners to run their businesses efficiently and effectively.

With a valuation of $1.6 million, Woven has already made a significant impact in the business management startup space in Indianapolis. The support of well-known brands further validates the effectiveness and reliability of Woven’s platform. As businesses continue to navigate the challenges of managing multiple locations and franchise operations, Woven stands out as a top choice for streamlining processes and optimizing operations.

Top Tech Startup in Indianapolis: DemandJump

DemandJump, an Indianapolis-based tech startup, is making waves in the world of customer acquisition. Specializing in cutting-edge software powered by artificial intelligence, DemandJump provides marketers with actionable data and insights to maximize their return on investment.

With DemandJump’s innovative customer acquisition software, marketers gain a holistic view of data and target market behavior. This enables them to make data-driven decisions, optimize their marketing strategies, and ultimately achieve greater success in their campaigns.

Founded in 2015, DemandJump has quickly established itself as a prominent player in the Indianapolis startup scene. Their dedication to harnessing the power of artificial intelligence to drive customer acquisition sets them apart from their competitors.

As artificial intelligence continues to shape the future of marketing, DemandJump’s innovative software positions them at the forefront of this technological advancement. By leveraging the power of AI, DemandJump empowers marketers to stay ahead of the competition and deliver exceptional results.

The Benefits of DemandJump’s Customer Acquisition Software

  • AI-powered software provides actionable data and insights
  • Enhances decision-making and marketing strategy optimization
  • Gives a holistic view of data and target market behavior
  • Harvests artificial intelligence for greater customer acquisition success

With its commitment to innovation and customer-centric solutions, DemandJump continues to provide marketers with the tools they need to succeed in an increasingly competitive digital landscape. As the demand for customer acquisition software powered by artificial intelligence grows, DemandJump is positioned to remain a leader in the industry.

Company Founded Location
DemandJump 2015 Indianapolis, Indiana


Indianapolis boasts a thriving startup community that is home to some of the best emerging companies in 2023. With a diverse range of industries represented, these startups are driving entrepreneurship in the city and contributing to the creation of a dynamic startup ecosystem.

Supported by investors and a collaborative startup community, Indianapolis startups have a bright future ahead. Their innovative ideas and disruptive solutions are making waves and having a positive impact on the city’s economy.

As these emerging companies continue to grow and evolve, it’s crucial to keep an eye on their progress. The Indianapolis startup scene is constantly evolving, and these startups are at the forefront of that growth. By staying connected to the startup community and following the journey of these best startups in Indianapolis, you can gain valuable insights into the future of the city’s entrepreneurial landscape.


What industries do these emerging startups in Indianapolis belong to?

These startups span various industries, including biotechnology, supply chain management, business management, and more.

What is the focus of MBX Biosciences?

MBX Biosciences focuses on developing therapies to treat rare endocrine diseases where there is inadequate treatment available.

How much funding has MBX Biosciences raised?

MBX Biosciences has raised $115 million to advance their Precision Endocrine Peptides.

What does PAXAFE specialize in?

PAXAFE leverages intelligent hardware, prediction models, and data algorithms to provide supply chain solutions.

How much funding did PAXAFE raise in early 2022?

PAXAFE raised $1.5 million in early 2022 to expand its customer base.

What does Woven offer?

Woven provides a multi-unit business management platform for franchisees and independent owners.

Which industries does Woven serve?

Woven serves industries such as spa, salon, retail, gym, and fitness, with notable brands already onboard.

What does DemandJump specialize in?

DemandJump specializes in customer acquisition software.

How does DemandJump’s software work?

DemandJump’s software uses artificial intelligence to provide marketers with actionable data and insights to maximize their return on investment.

When was DemandJump founded?

DemandJump was founded in 2015 and has already made a name for itself in the Indianapolis startup scene.

What is the significance of the emerging startups in Indianapolis?

The emerging startups in Indianapolis are driving the city’s entrepreneurship and creating a dynamic startup ecosystem.

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